Gain-of-function, focal segmental glomerulosclerosis Trpc6 mutation minimally affects susceptibility to renal injury in several mouse models

Mutations in TRPC6 are a cause of autosomal dominant focal segmental glomerulosclerosis in humans.Many of these mutations are known to have a gain-of-function effect on the non-specific cation channel function of TRPC6.In vitro studies have Medical and Ambulatory supplies / Gloves suggested these mutations affect several signaling pathways, but in

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Do social inequalities in health widen or converge with age? Longitudinal evidence from three cohorts in the West of Scotland

Abstract Background Existing studies are divided as to whether social inequalities in health widen or converge as people age.In part this is due to reliance on cross-sectional data, but also among longitudinal studies to differences in the measurement of both socioeconomic status (SES) and health and in the treatment of survival effects.The aim of

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Optimal Energy Management for Renewable Energy Microgrids

This paper deals with some issues related to optimal operation of microgrids, which are a group of loads, generators and energy storage systems that can be managed isolated or connected to the main grid, in a coordinated way in order to reliably supply electricity.The control problems and solution are addressed Wreaths both for optimal dispatch and

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